Liquid Chromatograph-Mass Spectrometry

LC/MS is becoming nowadays a routine tool in many application fields. It provides a solution with high selectivity, reliability, productivity and sensitivity requested in the areas of pharmaceuticals, food safety, chemicals, environmental analysis, as well as clinical. Shimadzu is offering a complete range from single quadrupole system, triple quadrupole systems to High Resolution MS system.

Shimadzu's LC/MS (Liquid Chromatograph-Mass Spectrometry) systems have created a new trend in the LCMS world, associating very fast polarity switching to fast scanning, low dwell time and pause time, while increasing sensitivity and data quality. This results in a powerful range enabling more compounds to be screened in less runs. It enables qualitative and quantitative analysis and, in fine, improves return of investment for all laboratories.

Time of Flight Instruments (Q-TOF)


Quadrupole Time-of-Flight Liquid Chromatograph Mass Spectrometer The LCMS-...

Triple Quadrupole LC-MS/MS Instruments


The LCMS-8060NX is a triple quadrupole mass spectrometer with world-class sensitivity and detection speeds. It boasts increased robustness and ease of use as well as Analytical Intelligence to maximize your laboratory’s output.


The LCMS-8060 is a ground breaking innovation in mass spectrometry helping to transform LC/MS/MS...


Experience a New Realm of High-Sensitivity & High-Speed Performance...


Accomplishes Both High Sensitivity and Ultra-High-Speed Detection   Equipped with a...


LCMS-8040 Enhanced Sensitivity  ...

Single Quadrupole LCMS Instruments


Ultra high-speed mass spectrometer compatible for the first time with ultra high-speed liquid...


Direct Probe Ionization Mass Spectrometer. The DPiMS-2020 is a single quadrupole mass...

Single Quad Preparative LCMS

Utilizing patented ultrafast technology, the LCMS-2020 mass spectrometer delivers more information about your preparative runs, and enables you to collect the right peak.

LCMS Medical Devices

LCMS In Vitro Diagnostic (IVD) Medical Devices

 Mass Spectrometry and Liquid Chromatography components for in vitro diagnostic applications

Solutions/Accessories for LCMS TQ & HRMS

CLAM - 2030

Fully Automated Sample Preparation Module for LCMS™ Based on Shimadzu's Extensive Experience...

C2MAP System

New Cell Culture Media Analysis Platform for Fundamental Research and...

Direct Probe Ionization Mass Spectrometer Kit

PESI ion source for LCMS TQ for direct analysis of sample without sample prep and separation ...

Nexera MX

Higher throughput is of the utmost importance to laboratory efficiency and profitability. Nexera MX...

Nexera Mikros

Micro: Above and Beyond Nano   The High Sensitivity You Expect from a Low Flow...

LDTD™ Ion Source Option for LCMS-8050/8060

The laser diode thermal desorption (LDTD)™ ion source as option for the LCMS TQ range ...

Trap-Free 2D LC/MS sytem for Quadrupole LCMS

A dedicated solution for impurities quantitation in Pharmaceutical field ...


The DPiMS QT probe electrospray ionization kit is attached to a quadrupole time-of-flight MS ...

LC-MS Columns & Consumables


LabSolutions Insight Library Screening

LC/MS/MS Screening Software

Solution System Packages

Sample preparation tools

LC-MS webinars

LC-MS Method Development Part 1: Differences from LC

This webinar is designed for people who are new to LC-MS/MS to give them a grounding in the differences from LC before moving onto more in-depth discussions about method development.


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LC-MS Method Development Part 2

This second session will cover the objectives and strategies to use for successful LC-MS(MS) method development. For beginners, we suggest you watch Session 1 before attending this session.



Simultaneous Analysis of COVID-19 Drug Candidates in Human Plasma by LC-MS/MS

In 2019, the COVID19 caught the world almost by surprise. Its relentless spread over the world forced authorities to act rapidly to find an adequate treatment. Besides drastic measure taken to lockdown half world population, some drugs targeting single strand RNA viruses, Malaria or even bacterials stains were propelled to FDA fast track of testing and approval to fight this new threat. Lacking deep phase I-II studies, clinical centers and hospitals had to set their own protocol to administer the treatment. Since many bioanalytical labs were equipped with LCMS/MS, corresponding stable isotope labeled standards availability became critical to monitor the drugs. We report here the analytical method developed by Alsachim using the molecules synthesized at our facilities.




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