LabSolutions Insight Library Screening :MRM Spectrum Mode
Using ONE concept
ONE Instrument
ONE Injection
ONE Workflow
to achieve two goals at once
High-Sensitivity Quantitation and High-Confidence Identification in ONE Run
Efficient
Streamlined
Reliable
Cost-Effective
Quantify and Identify using MRM Spectrum Mode
Step 1: Acquire data for all-available MRM (ion fragment) transitions
MRM Spectrum Mode
- Obtains same signal intensity for quantitation as conventional 2-MRM method
- Achieves uncompromised sensitivity with Shimadzu high-speed UFMS
Step 2: Generate the spectrum
Each fragment ion is optimized for the highest response giving a high-sensitivity mass spectrum.
Step 3: Compare with MRM library spectrum
MRM Spectrum Mode
- Achieves much higher confidence in compound identification than product ion scan.
- Reduces the possibility of false positive and false negative reporting to accelerate the data review process.
In Comparison to Existing Screening and Identification Workflows
Resources on MRM Spectrum Mode
Download these resources to learn more on MRM Spectrum Mode and find out how to apply it to accelerate your screening and identification workflow.
Application Notes
Peer-Reviewed Journal Publications
Fully Automated Forensic Routine Dried Blood Spot Screening for Workplace Testing
Gaugler, S.; Al-Mazroua, M. K. et al., Journal of Analytical Toxicology,
Published: 01 October 2018.
Fully Automated Drug Screening of Dried Blood Spots using Online LC-MS/MS Analysis
Gaugler, S.; Rykl, J. et al., Journal of Applied Bioanalysis, 2018, 4(1), 7-15.
Infographic
